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Detection of recurrent copy number alterations in the genome: taking among-subject heterogeneity seriously
BACKGROUND: Alterations in the number of copies of genomic DNA that are common or recurrent among diseased individuals are likely to contain disease-critical genes. Unfortunately, defining common or recurrent copy number alteration (CNA) regions remains a challenge. Moreover, the heterogeneous natur...
Autores principales: | Rueda, Oscar M, Diaz-Uriarte, Ramon |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760535/ https://www.ncbi.nlm.nih.gov/pubmed/19775444 http://dx.doi.org/10.1186/1471-2105-10-308 |
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