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The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma

BACKGROUND: Gambogic acid (GA) is a major active ingredient of gamboge, a widely used traditional Chinese medicine that has been reported to be a potent cytotoxic agent against some malignant tumors. Many studies have shown that the NF-kappa B signaling pathway plays an important role in anti-apopto...

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Detalles Bibliográficos
Autores principales: He, Di, Xu, Qin, Yan, Ming, Zhang, Ping, Zhou, Xiaojian, Zhang, Zhiyuan, Duan, Wenhu, Zhong, Laiping, Ye, Dongxia, Chen, Wantao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760578/
https://www.ncbi.nlm.nih.gov/pubmed/19778460
http://dx.doi.org/10.1186/1471-2407-9-343