Fibroblasts from patients with Diamond-Blackfan anaemia show abnormal expression of genes involved in protein synthesis, amino acid metabolism and cancer

BACKGROUND: Diamond-Blackfan anaemia (DBA) is a rare inherited red cell hypoplasia characterised by a defect in the maturation of erythroid progenitors and in some cases associated with malformations. Patients have an increased risk of solid tumors. Mutations have been found in several ribosomal pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Avondo, Federica, Roncaglia, Paola, Crescenzio, Nicoletta, Krmac, Helena, Garelli, Emanuela, Armiraglio, Marta, Castagnoli, Carlotta, Campagnoli, Maria Francesca, Ramenghi, Ugo, Gustincich, Stefano, Santoro, Claudio, Dianzani, Irma
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760583/
https://www.ncbi.nlm.nih.gov/pubmed/19765279
http://dx.doi.org/10.1186/1471-2164-10-442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760583/
https://www.ncbi.nlm.nih.gov/pubmed/19765279
http://dx.doi.org/10.1186/1471-2164-10-442

Ejemplares similares