Fibroblasts from patients with Diamond-Blackfan anaemia show abnormal expression of genes involved in protein synthesis, amino acid metabolism and cancer

BACKGROUND: Diamond-Blackfan anaemia (DBA) is a rare inherited red cell hypoplasia characterised by a defect in the maturation of erythroid progenitors and in some cases associated with malformations. Patients have an increased risk of solid tumors. Mutations have been found in several ribosomal pro...

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Detalles Bibliográficos
Autores principales: Avondo, Federica, Roncaglia, Paola, Crescenzio, Nicoletta, Krmac, Helena, Garelli, Emanuela, Armiraglio, Marta, Castagnoli, Carlotta, Campagnoli, Maria Francesca, Ramenghi, Ugo, Gustincich, Stefano, Santoro, Claudio, Dianzani, Irma
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760583/
https://www.ncbi.nlm.nih.gov/pubmed/19765279
http://dx.doi.org/10.1186/1471-2164-10-442

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