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Eicosanoid Release Is Increased by Membrane Destabilization and CFTR Inhibition in Calu-3 Cells

The antiinflammatory protein annexin-1 (ANXA1) and the adaptor S100A10 (p11), inhibit cytosolic phospholipase A2 (cPLA2α) by direct interaction. Since the latter is responsible for the cleavage of arachidonic acid at membrane phospholipids, all three proteins modulate eicosanoid production. We have...

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Detalles Bibliográficos
Autores principales: Borot, Florence, Vieu, Diane-Lore, Faure, Grazyna, Fritsch, Janine, Colas, Julien, Moriceau, Sandra, Baudouin-Legros, Maryvonne, Brouillard, Franck, Ayala-Sanmartin, Jesus, Touqui, Lhousseine, Chanson, Marc, Edelman, Aleksander, Ollero, Mario
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760709/
https://www.ncbi.nlm.nih.gov/pubmed/19847291
http://dx.doi.org/10.1371/journal.pone.0007116