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Eicosanoid Release Is Increased by Membrane Destabilization and CFTR Inhibition in Calu-3 Cells
The antiinflammatory protein annexin-1 (ANXA1) and the adaptor S100A10 (p11), inhibit cytosolic phospholipase A2 (cPLA2α) by direct interaction. Since the latter is responsible for the cleavage of arachidonic acid at membrane phospholipids, all three proteins modulate eicosanoid production. We have...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760709/ https://www.ncbi.nlm.nih.gov/pubmed/19847291 http://dx.doi.org/10.1371/journal.pone.0007116 |