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Potential Role of Sirtuin as a Therapeutic Target for Neurodegenerative Diseases
The sirtuins (SIRTs) are protein-modifying enzymes that are distributed ubiquitously in all organisms. SIRT1 is a mammalian homologue of yeast nicotinamide-adenine-dinucleotide-dependent deacetylase silent information regulator 2 (known as Sir2), which is the best-characterized SIRT family member. I...
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| Formato: | Texto |
| Lenguaje: | English |
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Korean Neurological Association
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760716/ https://www.ncbi.nlm.nih.gov/pubmed/19826562 http://dx.doi.org/10.3988/jcn.2009.5.3.120 |