p53 Amino-Terminus Region (1–125) Stabilizes and Restores Heat Denatured p53 Wild Phenotype

BACKGROUND: The intrinsically disordered N-ter domain (NTD) of p53 encompasses approximately hundred amino acids that contain a transactivation domain (1–73) and a proline-rich domain (64–92) and is responsible for transactivation function and apoptosis. It also possesses an auto-inhibitory function...

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Detalles Bibliográficos
Autores principales: Sharma, Anuj Kumar, Ali, Amjad, Gogna, Rajan, Singh, Amir Kumar, Pati, Uttam
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760748/
https://www.ncbi.nlm.nih.gov/pubmed/19847292
http://dx.doi.org/10.1371/journal.pone.0007159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760748/
https://www.ncbi.nlm.nih.gov/pubmed/19847292
http://dx.doi.org/10.1371/journal.pone.0007159

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