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Efficacy of Short-Course AZT Plus 3TC to Reduce Nevirapine Resistance in the Prevention of Mother-to-Child HIV Transmission: A Randomized Clinical Trial

BACKGROUND: Single-dose nevirapine (sdNVP)—which prevents mother-to-child transmission of HIV—selects non-nucleoside reverse-transcriptase inhibitor (NNRTI) resistance mutations in the majority of women and HIV-infected infants receiving it. This open-label, randomised trial examined the efficacy of...

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Detalles Bibliográficos
Autores principales: McIntyre, James A., Hopley, Mark, Moodley, Daya, Eklund, Marie, Gray, Glenda E., Hall, David B., Robinson, Patrick, Mayers, Douglas, Martinson, Neil A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760761/
https://www.ncbi.nlm.nih.gov/pubmed/19859531
http://dx.doi.org/10.1371/journal.pmed.1000172