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The ADMR Receptor Mediates the Effects of Adrenomedullin on Pancreatic Cancer Cells and on Cells of the Tumor Microenvironment

BACKGROUND: Adrenomedullin (AM) is highly expressed in pancreatic cancer and stimulates pancreatic cancer cells leading to increased tumor growth and metastasis. The current study examines the role of specific AM receptors on tumor and cells resembling the tumor microenvironment (human pancreatic st...

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Detalles Bibliográficos
Autores principales: Ramachandran, Vijaya, Arumugam, Thiruvengadam, Langley, Robert, Hwang, Rosa F., Vivas-Mejia, Pablo, Sood, Anil K., Lopez-Berestein, Gabriel, Logsdon, Craig D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760778/
https://www.ncbi.nlm.nih.gov/pubmed/19847298
http://dx.doi.org/10.1371/journal.pone.0007502