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Chemical synthesis, DNA incorporation and biological study of a new photocleavable 2′-deoxyadenosine mimic

The phototriggered cleavage of chemical bonds has found numerous applications in biology, particularly in the field of gene sequencing through photoinduced DNA strand scission. However, only a small number of modified nucleosides that are able to cleave DNA at selected positions have been reported i...

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Detalles Bibliográficos
Autores principales: Berthet, Nathalie, Crey-Desbiolles, Caroline, Kotera, Mitsuharu, Dumy, Pascal
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760783/
https://www.ncbi.nlm.nih.gov/pubmed/19586934
http://dx.doi.org/10.1093/nar/gkp562