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Chemical synthesis, DNA incorporation and biological study of a new photocleavable 2′-deoxyadenosine mimic
The phototriggered cleavage of chemical bonds has found numerous applications in biology, particularly in the field of gene sequencing through photoinduced DNA strand scission. However, only a small number of modified nucleosides that are able to cleave DNA at selected positions have been reported i...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760783/ https://www.ncbi.nlm.nih.gov/pubmed/19586934 http://dx.doi.org/10.1093/nar/gkp562 |