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LSM1 over-expression in Saccharomyces cerevisiae depletes U6 snRNA levels
Lsm1 is a component of the Lsm1-7 complex involved in cytoplasmic mRNA degradation. Lsm1 is over-expressed in multiple tumor types, including over 80% of pancreatic tumors, and increased levels of Lsm1 protein have been shown to induce carcinogenic effects. Therefore, understanding the perturbations...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760792/ https://www.ncbi.nlm.nih.gov/pubmed/19596813 http://dx.doi.org/10.1093/nar/gkp572 |