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Dissecting protein-induced DNA looping dynamics in real time

Many proteins that interact with DNA perform or enhance their specific functions by binding simultaneously to multiple target sites, thereby inducing a loop in the DNA. The dynamics and energies involved in this loop formation influence the reaction mechanism. Tethered particle motion has proven a p...

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Detalles Bibliográficos
Autores principales: Laurens, Niels, Bellamy, Stuart R. W., Harms, August F., Kovacheva, Yana S., Halford, Stephen E., Wuite, Gijs J. L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760800/
https://www.ncbi.nlm.nih.gov/pubmed/19586932
http://dx.doi.org/10.1093/nar/gkp570