Determination of the target nucleosides for members of two families of 16S rRNA methyltransferases that confer resistance to partially overlapping groups of aminoglycoside antibiotics

The 16S ribosomal RNA methyltransferase enzymes that modify nucleosides in the drug binding site to provide self-resistance in aminoglycoside-producing micro-organisms have been proposed to comprise two distinct groups of S-adenosyl-l-methionine (SAM)-dependent RNA enzymes, namely the Kgm and Kam fa...

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Detalles Bibliográficos
Autores principales: Savic, Miloje, Lovrić, Josip, Tomic, Tatjana Ilic, Vasiljevic, Branka, Conn, Graeme L.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760815/
https://www.ncbi.nlm.nih.gov/pubmed/19589804
http://dx.doi.org/10.1093/nar/gkp575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760815/
https://www.ncbi.nlm.nih.gov/pubmed/19589804
http://dx.doi.org/10.1093/nar/gkp575

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