Akt1 Intramitochondrial Cycling Is a Crucial Step in the Redox Modulation of Cell Cycle Progression

Akt is a serine/threonine kinase involved in cell proliferation, apoptosis, and glucose metabolism. Akt is differentially activated by growth factors and oxidative stress by sequential phosphorylation of Ser(473) by mTORC2 and Thr(308) by PDK1. On these bases, we investigated the mechanistic connect...

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Detalles Bibliográficos
Autores principales: Antico Arciuch, Valeria Gabriela, Galli, Soledad, Franco, María Clara, Lam, Philip Y., Cadenas, Enrique, Carreras, María Cecilia, Poderoso, Juan José
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761088/
https://www.ncbi.nlm.nih.gov/pubmed/19844585
http://dx.doi.org/10.1371/journal.pone.0007523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761088/
https://www.ncbi.nlm.nih.gov/pubmed/19844585
http://dx.doi.org/10.1371/journal.pone.0007523

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