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Comparative in vivo bioequivalence and in vitro dissolution of two valproic acid sustained-release formulations
OBJECTIVE: A study was conducted to establish the bioequivalence between different sustained-release formulations of valproic acid (Depakene R and Selenica R), which were developed in Japan. MATERIALS AND METHODS: The clinical investigation was designed in a randomized, crossover fashion with a sing...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761171/ https://www.ncbi.nlm.nih.gov/pubmed/19920901 |