Antidiabetic Bis-Maltolato-OxoVanadium(IV): Conversion of inactive trans- to bioactive cis-BMOV for possible binding to target PTP-1B

The postulated transition of Bis-Maltolato-OxoVanadium(IV) (BMOV) from its inactive trans- into its cis-aquo-BMOV isomeric form in solution was simulated by means of computational molecular modeling. The rotational barrier was calculated with DFT – B3LYP under a stepwise optimization protocol with S...

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Detalles Bibliográficos
Autores principales: Scior, Thomas, Mack, Hans-Georg, García, José Antonio Guevara, Koch, Wolfhard
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761195/
https://www.ncbi.nlm.nih.gov/pubmed/19920909

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761195/
https://www.ncbi.nlm.nih.gov/pubmed/19920909

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