Conserved principles of mammalian transcriptional regulation revealed by RNA half-life

RNA levels in a cell are regulated by the relative rates of RNA synthesis and decay. We recently developed a new approach for measuring both RNA synthesis and decay in a single experimental setting by biosynthetic labeling of newly transcribed RNA. Here, we show that this provides measurements of RN...

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Detalles Bibliográficos
Autores principales: Friedel, Caroline C., Dölken, Lars, Ruzsics, Zsolt, Koszinowski, Ulrich H., Zimmer, Ralf
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761256/
https://www.ncbi.nlm.nih.gov/pubmed/19561200
http://dx.doi.org/10.1093/nar/gkp542

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761256/
https://www.ncbi.nlm.nih.gov/pubmed/19561200
http://dx.doi.org/10.1093/nar/gkp542

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