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Conserved principles of mammalian transcriptional regulation revealed by RNA half-life
RNA levels in a cell are regulated by the relative rates of RNA synthesis and decay. We recently developed a new approach for measuring both RNA synthesis and decay in a single experimental setting by biosynthetic labeling of newly transcribed RNA. Here, we show that this provides measurements of RN...
Autores principales: | Friedel, Caroline C., Dölken, Lars, Ruzsics, Zsolt, Koszinowski, Ulrich H., Zimmer, Ralf |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761256/ https://www.ncbi.nlm.nih.gov/pubmed/19561200 http://dx.doi.org/10.1093/nar/gkp542 |
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