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Crystal structure of DNA gyrase B′ domain sheds lights on the mechanism for T-segment navigation

DNA gyrase is an indispensible marvelous molecular machine in manipulating the DNA topology for the prokaryotes. In the ‘two-gate’ mechanism of DNA topoisomerase, T-segment navigation from N- to DNA-gate is a critical step, but the structural basis supporting this scheme is unclear. The crystal stru...

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Detalles Bibliográficos
Autores principales: Fu, Guangsen, Wu, Jinjun, Liu, Wei, Zhu, Deyu, Hu, Yonglin, Deng, Jiaoyu, Zhang, Xian-En, Bi, Lijun, Wang, Da-Cheng
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761264/
https://www.ncbi.nlm.nih.gov/pubmed/19596812
http://dx.doi.org/10.1093/nar/gkp586