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Molecular dissection of the prototype foamy virus (PFV) RNA 5′-UTR identifies essential elements of a ribosomal shunt

The prototype foamy virus (PFV) is a nonpathogenic retrovirus that shows promise as a vector for gene transfer. The PFV (pre)genomic RNA starts with a long complex leader that can be folded into an elongated hairpin, suggesting an alternative strategy to cap-dependent linear scanning for translation...

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Detalles Bibliográficos
Autores principales: Schepetilnikov, Mikhail, Schott, Gregory, Katsarou, Konstantina, Thiébeauld, Odon, Keller, Mario, Ryabova, Lyubov A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761275/
https://www.ncbi.nlm.nih.gov/pubmed/19638424
http://dx.doi.org/10.1093/nar/gkp609