Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo(−) ) DNA polymerase

In our previous communication we reported the enzymatic recognition of unnatural imidazopyridopyrimidine:naphthyridine (Im:Na) base pairs, i.e. ImO(N):NaN(O) and ImN(O):NaO(N), using the Klenow fragment exo(−) [KF (exo(−))]. We describe herein the successful results of (i) improved enzymatic recogni...

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Detalles Bibliográficos
Autores principales: Ogata, Shintaro, Takahashi, Mayumi, Minakawa, Noriaki, Matsuda, Akira
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Chemistry and Synthetic Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761277/
https://www.ncbi.nlm.nih.gov/pubmed/19628664
http://dx.doi.org/10.1093/nar/gkp611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761277/
https://www.ncbi.nlm.nih.gov/pubmed/19628664
http://dx.doi.org/10.1093/nar/gkp611

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