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Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by Deep Vent (exo(−) ) DNA polymerase
In our previous communication we reported the enzymatic recognition of unnatural imidazopyridopyrimidine:naphthyridine (Im:Na) base pairs, i.e. ImO(N):NaN(O) and ImN(O):NaO(N), using the Klenow fragment exo(−) [KF (exo(−))]. We describe herein the successful results of (i) improved enzymatic recogni...
Autores principales: | Ogata, Shintaro, Takahashi, Mayumi, Minakawa, Noriaki, Matsuda, Akira |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761277/ https://www.ncbi.nlm.nih.gov/pubmed/19628664 http://dx.doi.org/10.1093/nar/gkp611 |
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