The accessory subunit of mitochondrial DNA polymerase γ determines the DNA content of mitochondrial nucleoids in human cultured cells

The accessory subunit of mitochondrial DNA polymerase γ, POLGβ, functions as a processivity factor in vitro. Here we show POLGβ has additional roles in mitochondrial DNA metabolism. Mitochondrial DNA is arranged in nucleoprotein complexes, or nucleoids, which often contain multiple copies of the mit...

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Detalles Bibliográficos
Autores principales: Di Re, M., Sembongi, H., He, J., Reyes, A., Yasukawa, T., Martinsson, P., Bailey, L. J., Goffart, S., Boyd-Kirkup, J. D., Wong, T. S., Fersht, A. R., Spelbrink, J. N., Holt, I. J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761280/
https://www.ncbi.nlm.nih.gov/pubmed/19625489
http://dx.doi.org/10.1093/nar/gkp614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761280/
https://www.ncbi.nlm.nih.gov/pubmed/19625489
http://dx.doi.org/10.1093/nar/gkp614

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