Assessment of Metabolome Annotation Quality: A Method for Evaluating the False Discovery Rate of Elemental Composition Searches

BACKGROUND: In metabolomics researches using mass spectrometry (MS), systematic searching of high-resolution mass data against compound databases is often the first step of metabolite annotation to determine elemental compositions possessing similar theoretical mass numbers. However, incorrect hits...

Descripción completa

Detalles Bibliográficos
Autores principales: Matsuda, Fumio, Shinbo, Yoko, Oikawa, Akira, Hirai, Masami Yokota, Fiehn, Oliver, Kanaya, Shigehiko, Saito, Kazuki
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761541/
https://www.ncbi.nlm.nih.gov/pubmed/19847304
http://dx.doi.org/10.1371/journal.pone.0007490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761541/
https://www.ncbi.nlm.nih.gov/pubmed/19847304
http://dx.doi.org/10.1371/journal.pone.0007490

Ejemplares similares