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Protein Kinase D1 regulates Cofilin mediated F-actin reorganization and cell motility via Slingshot

Dynamic actin remodelling processes at the leading edge of migrating tumour cells are concerted events controlled by a fine-tuned temporal and spatial interplay of kinases and phosphatases. Actin severing is regulated by ADF/Cofilin which regulates stimulus-induced lamellipodia protrusion and direct...

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Detalles Bibliográficos
Autores principales: Eiseler, Tim, Döppler, Heike, Yan, Irene K., Kitatani, Kanae, Mizuno, Kensaku, Storz, Peter
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761768/
https://www.ncbi.nlm.nih.gov/pubmed/19329994
http://dx.doi.org/10.1038/ncb1861