Do the mutations of C1GALT1C1 gene play important roles in the genetic susceptibility to Chinese IgA nephropathy?

BACKGROUND: The deficiency of β1,3 galactose in hinge region of IgA1 molecule played a pivotal role in pathogenesis of IgA nephropathy (IgAN). Cosmc, encoded by C1GALT1C1 gene, was indispensable to β1,3 galactosylation of IgA1. We designed a serial study to investigate the relationship between the m...

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Detalles Bibliográficos
Autores principales: Li, Gui-Sen, Nie, Guang-Jun, Zhang, Hong, LV, Ji-Cheng, Shen, Yan, Wang, Hai-Yan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761879/
https://www.ncbi.nlm.nih.gov/pubmed/19778426
http://dx.doi.org/10.1186/1471-2350-10-101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761879/
https://www.ncbi.nlm.nih.gov/pubmed/19778426
http://dx.doi.org/10.1186/1471-2350-10-101

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