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Dysbindin Modulates Prefrontal Cortical Glutamatergic Circuits and Working Memory Function in Mice

Behavioral genetic studies of humans have associated variation in the DTNBP1 gene with schizophrenia and its cognitive deficit phenotypes. The protein coded for by DTNBP1, dysbindin, is expressed within forebrain glutamatergic neurons, where it interacts with proteins involved in vesicular trafficki...

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Detalles Bibliográficos
Autores principales: Jentsch, J. David, Trantham-Davidson, Heather, Jairl, Corey, Tinsley, Matthew, Cannon, Tyrone D, Lavin, Antonieta
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762021/
https://www.ncbi.nlm.nih.gov/pubmed/19641486
http://dx.doi.org/10.1038/npp.2009.90