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Mutations in the Caenorhabditis elegans U2AF Large Subunit UAF-1 Alter the Choice of a 3′ Splice Site In Vivo

The removal of introns from eukaryotic RNA transcripts requires the activities of five multi-component ribonucleoprotein complexes and numerous associated proteins. The lack of mutations affecting splicing factors essential for animal survival has limited the study of the in vivo regulation of splic...

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Detalles Bibliográficos
Autores principales: Ma, Long, Horvitz, H. Robert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762039/
https://www.ncbi.nlm.nih.gov/pubmed/19893607
http://dx.doi.org/10.1371/journal.pgen.1000708