Molecular mechanisms that enhance synapse stability despite persistent disruption of the spectrin/ankyrin/microtubule cytoskeleton

Loss of spectrin or ankyrin in the presynaptic motoneuron disrupts the synaptic microtubule cytoskeleton and leads to disassembly of the neuromuscular junction (NMJ). Here, we demonstrate that NMJ disassembly after loss of α-spectrin can be suppressed by expression of a Wld(S) transgene, providing e...

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Detalles Bibliográficos
Autores principales: Massaro, Catherine M., Pielage, Jan, Davis, Graeme W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762090/
https://www.ncbi.nlm.nih.gov/pubmed/19805631
http://dx.doi.org/10.1083/jcb.200903166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762090/
https://www.ncbi.nlm.nih.gov/pubmed/19805631
http://dx.doi.org/10.1083/jcb.200903166

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