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Relative contributions of chromatin and kinetochores to mitotic spindle assembly

During mitosis and meiosis in animal cells, chromosomes actively participate in spindle assembly by generating a gradient of Ran guanosine triphosphate (RanGTP). A high concentration of RanGTP promotes microtubule nucleation and stabilization in the vicinity of chromatin. However, the relative contr...

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Detalles Bibliográficos
Autores principales: O'Connell, Christopher B., Lončarek, Jadranka, Kaláb, Petr, Khodjakov, Alexey
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762104/
https://www.ncbi.nlm.nih.gov/pubmed/19805628
http://dx.doi.org/10.1083/jcb.200903076