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Tipping the Balance: Robustness of Tip Cell Selection, Migration and Fusion in Angiogenesis

Vascular abnormalities contribute to many diseases such as cancer and diabetic retinopathy. In angiogenesis new blood vessels, headed by a migrating tip cell, sprout from pre-existing vessels in response to signals, e.g., vascular endothelial growth factor (VEGF). Tip cells meet and fuse (anastomosi...

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Detalles Bibliográficos
Autores principales: Bentley, Katie, Mariggi, Giovanni, Gerhardt, Holger, Bates, Paul A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762315/
https://www.ncbi.nlm.nih.gov/pubmed/19876379
http://dx.doi.org/10.1371/journal.pcbi.1000549