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Tipping the Balance: Robustness of Tip Cell Selection, Migration and Fusion in Angiogenesis
Vascular abnormalities contribute to many diseases such as cancer and diabetic retinopathy. In angiogenesis new blood vessels, headed by a migrating tip cell, sprout from pre-existing vessels in response to signals, e.g., vascular endothelial growth factor (VEGF). Tip cells meet and fuse (anastomosi...
Autores principales: | Bentley, Katie, Mariggi, Giovanni, Gerhardt, Holger, Bates, Paul A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762315/ https://www.ncbi.nlm.nih.gov/pubmed/19876379 http://dx.doi.org/10.1371/journal.pcbi.1000549 |
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