Evaluation of genome coverage and fidelity of multiple displacement amplification from single cells by SNP array

The scarce amount of DNA contained in a singe cell is a limiting factor for clinical application of preimplantation genetic diagnosis mainly due to the risk of misdiagnosis caused by allele dropout and the difficulty in obtaining copy number variations in all 23 pairs of chromosomes. Multiple displa...

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Detalles Bibliográficos
Autores principales: Ling, Jiawei, Zhuang, Guanglun, Tazon-Vega, Barbara, Zhang, Chenhui, Cao, Baoqiang, Rosenwaks, Zev, Xu, Kangpu
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762374/
https://www.ncbi.nlm.nih.gov/pubmed/19671595
http://dx.doi.org/10.1093/molehr/gap066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762374/
https://www.ncbi.nlm.nih.gov/pubmed/19671595
http://dx.doi.org/10.1093/molehr/gap066

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