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Alternative Processing of Primary microRNA Transcripts by Drosha Generates 5′ End Variation of Mature microRNA
BACKGROUND: It is generally believed that the miRNA processing machinery ensures the generation of a mature miRNA with a fixed sequence, particularly at its 5′ end. However, we and others have recently noted that the ends of a given mature miRNA are not absolutely fixed, but subject to variation. Ne...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762519/ https://www.ncbi.nlm.nih.gov/pubmed/19859542 http://dx.doi.org/10.1371/journal.pone.0007566 |