Different molecular mechanisms causing 9p21 deletions in acute lymphoblastic leukemia of childhood

Deletion of chromosome 9p21 is a crucial event for the development of several cancers including acute lymphoblastic leukemia (ALL). Double strand breaks (DSBs) triggering 9p21 deletions in ALL have been reported to occur at a few defined sites by illegitimate action of the V(D)J recombination activa...

Descripción completa

Detalles Bibliográficos
Autores principales: Novara, Francesca, Beri, Silvana, Bernardo, Maria Ester, Bellazzi, Riccardo, Malovini, Alberto, Ciccone, Roberto, Cometa, Angela Maria, Locatelli, Franco, Giorda, Roberto, Zuffardi, Orsetta
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762534/
https://www.ncbi.nlm.nih.gov/pubmed/19484265
http://dx.doi.org/10.1007/s00439-009-0689-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762534/
https://www.ncbi.nlm.nih.gov/pubmed/19484265
http://dx.doi.org/10.1007/s00439-009-0689-7

Ejemplares similares