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Evasion by Stealth: Inefficient Immune Activation Underlies Poor T Cell Response and Severe Disease in SARS-CoV-Infected Mice

Severe Acute Respiratory Syndrome caused substantial morbidity and mortality during the 2002–2003 epidemic. Many of the features of the human disease are duplicated in BALB/c mice infected with a mouse-adapted version of the virus (MA15), which develop respiratory disease with high morbidity and mor...

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Detalles Bibliográficos
Autores principales: Zhao, Jincun, Zhao, Jingxian, Van Rooijen, Nico, Perlman, Stanley
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762542/
https://www.ncbi.nlm.nih.gov/pubmed/19851468
http://dx.doi.org/10.1371/journal.ppat.1000636