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COP9 Limits Dendritic Branching via Cullin3-Dependent Degradation of the Actin-Crosslinking BTB-Domain Protein Kelch

Components of the COP9 signalosome (CSN), a key member of the conserved 26S proteasome degradation pathway, have been detected to be altered in patients of several debilitating syndromes. These findings suggest that CSN acts in neural circuits, but the exact function of CSN in brain remains unidenti...

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Detalles Bibliográficos
Autores principales: Djagaeva, Inna, Doronkin, Sergey
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762543/
https://www.ncbi.nlm.nih.gov/pubmed/19859546
http://dx.doi.org/10.1371/journal.pone.0007598