C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer

SARS coronavirus main protease (M(pro)) plays an essential role in the extensive proteolytic processing of the viral polyproteins (pp1a and pp1ab), and it is an important target for anti-SARS drug development. We have reported that both the M(pro) C-terminal domain alone (M(pro)-C) and the N-finger...

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Detalles Bibliográficos
Autores principales: Zhong, Nan, Zhang, Shengnan, Xue, Fei, Kang, Xue, Zou, Peng, Chen, Jiaxuan, Liang, Chao, Rao, Zihe, Jin, Changwen, Lou, Zhiyong, Xia, Bin
Formato: Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2009
Materias:
Protein Structure Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762595/
https://www.ncbi.nlm.nih.gov/pubmed/19319935
http://dx.doi.org/10.1002/pro.76

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762595/
https://www.ncbi.nlm.nih.gov/pubmed/19319935
http://dx.doi.org/10.1002/pro.76

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