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C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer
SARS coronavirus main protease (M(pro)) plays an essential role in the extensive proteolytic processing of the viral polyproteins (pp1a and pp1ab), and it is an important target for anti-SARS drug development. We have reported that both the M(pro) C-terminal domain alone (M(pro)-C) and the N-finger...
Autores principales: | Zhong, Nan, Zhang, Shengnan, Xue, Fei, Kang, Xue, Zou, Peng, Chen, Jiaxuan, Liang, Chao, Rao, Zihe, Jin, Changwen, Lou, Zhiyong, Xia, Bin |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762595/ https://www.ncbi.nlm.nih.gov/pubmed/19319935 http://dx.doi.org/10.1002/pro.76 |
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