Cargando…

An aPKC-Exocyst Complex Controls Paxillin Phosphorylation and Migration through Localised JNK1 Activation

Atypical protein kinase C (aPKC) isoforms have been implicated in cell polarisation and migration through association with Cdc42 and Par6. In distinct migratory models, the Exocyst complex has been shown to be involved in secretory events and migration. By RNA interference (RNAi) we show that the po...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosse, Carine, Formstecher, Etienne, Boeckeler, Katrina, Zhao, Yingming, Kremerskothen, Joachim, White, Michael D., Camonis, Jacques H., Parker, Peter J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762617/
https://www.ncbi.nlm.nih.gov/pubmed/19885391
http://dx.doi.org/10.1371/journal.pbio.1000235