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The NADPH oxidase Nox4 restricts the replicative lifespan of human endothelial cells
The free radical theory of aging proposes that ROS (reactive oxygen species) are major driving forces of aging, and are also critically involved in cellular senescence. Besides the mitochondrial respiratory chain, alternative sources of ROS have been described that might contribute to cellular senes...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762686/ https://www.ncbi.nlm.nih.gov/pubmed/19681754 http://dx.doi.org/10.1042/BJ20090666 |