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The NADPH oxidase Nox4 restricts the replicative lifespan of human endothelial cells

The free radical theory of aging proposes that ROS (reactive oxygen species) are major driving forces of aging, and are also critically involved in cellular senescence. Besides the mitochondrial respiratory chain, alternative sources of ROS have been described that might contribute to cellular senes...

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Detalles Bibliográficos
Autores principales:	Lener, Barbara, Kozieł, Rafał, Pircher, Haymo, Hütter, Eveline, Greussing, Ruth, Herndler-Brandstetter, Dietmar, Hermann, Martin, Unterluggauer, Hermann, Jansen-Dürr, Pidder
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762686/ https://www.ncbi.nlm.nih.gov/pubmed/19681754 http://dx.doi.org/10.1042/BJ20090666

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