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Glucocorticoids can activate the α-ENaC gene promoter independently of SGK1

The role of SGK1 (serum- and glucocorticoid-induced protein kinase 1) in the glucocorticoid induction of α-ENaC (epithelial Na(+) channel α subunit) gene transcription was explored by monitoring the transcriptional activity of a luciferase-linked, α-ENaC reporter gene construct (pGL3-KR1) expressed...

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Detalles Bibliográficos
Autores principales: McTavish, Niall, Getty, Jennet, Burchell, Ann, Wilson, Stuart M.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762689/
https://www.ncbi.nlm.nih.gov/pubmed/19619128
http://dx.doi.org/10.1042/BJ20090366