Cargando…

Glucocorticoids can activate the α-ENaC gene promoter independently of SGK1

The role of SGK1 (serum- and glucocorticoid-induced protein kinase 1) in the glucocorticoid induction of α-ENaC (epithelial Na(+) channel α subunit) gene transcription was explored by monitoring the transcriptional activity of a luciferase-linked, α-ENaC reporter gene construct (pGL3-KR1) expressed...

Descripción completa

Detalles Bibliográficos
Autores principales:	McTavish, Niall, Getty, Jennet, Burchell, Ann, Wilson, Stuart M.
Formato:	Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762689/ https://www.ncbi.nlm.nih.gov/pubmed/19619128 http://dx.doi.org/10.1042/BJ20090366

Ejemplares similares

The N terminus of α-ENaC mediates ENaC cleavage and activation by furin
por: Kota, Pradeep, et al.
Publicado: (2018)

Activation of SGK1/ENaC Signaling Pathway Improves the Level of Decidualization in Unexplained Recurrent Spontaneous Abortion
por: Di, Xiaoqian, et al.
Publicado: (2023)

ENaC activation by proteases
por: Anand, Deepika, et al.
Publicado: (2022)

The Plant-Derived Glucocorticoid Receptor Agonist Endiandrin A Acts as Co-Stimulator of Colonic Epithelial Sodium Channels (ENaC) via SGK-1 and MAPKs
por: Kuntzsch, Dana, et al.
Publicado: (2012)

Pendrin abundance, subcellular distribution, and function are unaffected by either αENaC gene ablation or by increasing ENaC channel activity
por: Loffing, Johannes, et al.
Publicado: (2023)

ENaC in Cholinergic Brush Cells
por: Kandel, Chrissy, et al.
Publicado: (2018)

Expression of ENaC subunits in epithelia
por: Frindt, Gustavo, et al.
Publicado: (2022)

Rosiglitazone promotes ENaC-mediated alveolar fluid clearance in acute lung injury through the PPARγ/SGK1 signaling pathway
por: He, Jing, et al.
Publicado: (2019)

Shear force sensing of epithelial Na(+) channel (ENaC) relies on N-glycosylated asparagines in the palm and knuckle domains of αENaC
por: Knoepp, Fenja, et al.
Publicado: (2020)

Mambalgin-2 Inhibits Lung Adenocarcinoma Growth and Migration by Selective Interaction With ASIC1/α-ENaC/γ-ENaC Heterotrimer
por: Sudarikova, Anastasia V., et al.
Publicado: (2022)

Molecular Basis for Mambalgin-2 Interaction with Heterotrimeric α-ENaC/ASIC1a/γ-ENaC Channels in Cancer Cells
por: Lyukmanova, Ekaterina N., et al.
Publicado: (2023)

Endogenous Protease Activation of ENaC: Effect of Serine Protease Inhibition on ENaC Single Channel Properties
por: Adebamiro, Adedotun, et al.
Publicado: (2005)

The endothelial αENaC contributes to vascular endothelial function in vivo
por: Tarjus, Antoine, et al.
Publicado: (2017)

Regulation of ENaC trafficking in rat kidney
por: Frindt, Gustavo, et al.
Publicado: (2016)

ENaC/DEG in Tumor Development and Progression
por: Liu, Cui, et al.
Publicado: (2016)

Mineralocorticoid receptor-independent activation of ENaC in bile duct ligated mice
por: Wang, Xue-Ping, et al.
Publicado: (2023)

Hypercapnia Impairs ENaC Cell Surface Stability by Promoting Phosphorylation, Polyubiquitination and Endocytosis of β-ENaC in a Human Alveolar Epithelial Cell Line
por: Gwoździńska, Paulina, et al.
Publicado: (2017)

Aldosterone and vasopressin affect α- and γ-ENaC mRNA translation
por: Perlewitz, Andrea, et al.
Publicado: (2010)

Postprandial Effects on ENaC-Mediated Sodium Absorption
por: Blass, Gregory, et al.
Publicado: (2019)

Aldosterone Modulates the Association between NCC and ENaC
por: Wynne, Brandi M., et al.
Publicado: (2017)

ENaC in Salt-Sensitive Hypertension: Kidney and Beyond
por: Pitzer, Ashley L., et al.
Publicado: (2020)

CRISPR/Cas9 Mediated Knock Down of δ-ENaC Blunted the TNF-Induced Activation of ENaC in A549 Cells
por: Shabbir, Waheed, et al.
Publicado: (2021)

Function and phylogeny support the independent evolution of an ASIC-like Deg/ENaC channel in the Placozoa
por: Elkhatib, Wassim, et al.
Publicado: (2023)

Mechanosensitivity of the Epithelial Sodium Channel (ENaC): Controversy or Pseudocontroversy?
por: Rossier, Bernard C.
Publicado: (1998)

ENaC Proteolytic Regulation by Channel-activating Protease 2
por: García-Caballero, Agustín, et al.
Publicado: (2008)

There and back again: insulin, ENaC, and the cortical collecting duct
por: Pao, Alan C.
Publicado: (2016)

Does ENaC Work as Sodium Taste Receptor in Humans?
por: Bigiani, Albertino
Publicado: (2020)

Accessibility of ENaC extracellular domain central core residues
por: Zhang, Lei, et al.
Publicado: (2022)

The Absence of Endothelial Sodium Channel α (αENaC) Reduces Renal Ischemia/Reperfusion Injury
por: Tarjus, Antoine, et al.
Publicado: (2019)

Cleavage of endogenous γENaC and elevated abundance of αENaC are associated with increased Na(+) transport in response to apical fluid volume expansion in human H441 airway epithelial cells
por: Tan, Chong D., et al.
Publicado: (2011)

Therapeutic Effects of α1-Antitrypsin on Psedumonas aeruginosa Infection in ENaC Transgenic Mice
por: Nichols, David P., et al.
Publicado: (2015)

Synergistic Activation of ENaC by Three Membrane-bound Channel-activating Serine Proteases (mCAP1, mCAP2, and mCAP3) and Serum- and Glucocorticoid-regulated Kinase (Sgk1) in Xenopus Oocytes
por: Vuagniaux, Grégoire, et al.
Publicado: (2002)

ENaC–Membrane Interactions: Regulation of Channel Activity by Membrane Order
por: Awayda, Mouhamed S., et al.
Publicado: (2004)

Effect of ENaC Modulators on Rat Neural Responses to NaCl
por: Mummalaneni, Shobha, et al.
Publicado: (2014)

Dysregulation of ENaC in Animal Models of Nephrotic Syndrome and Liver Cirrhosis
por: Kim, Soo Wan
Publicado: (2006)

Increased ENaC activity during kidney preservation in Wisconsin solution
por: Khedr, Sherif, et al.
Publicado: (2019)

ENaC regulation by phospholipids and DGK explained through mathematical modeling
por: Olivença, Daniel V., et al.
Publicado: (2020)

Is the ENaC Dysregulation in CF an Effect of Protein-Lipid Interaction in the Membranes?
por: Strandvik, Birgitta
Publicado: (2021)

ENaC expression correlates with the acute furosemide‐induced K(+) excretion
por: Ayasse, Niklas, et al.
Publicado: (2021)

Proteolytic ENaC activation in health and disease—a complicated puzzle
por: Althaus, Mike, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pahkhrnj4lk1870jsufbou733h