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Top-hits for H1N1pdm Identified by Virtual Screening Using Ensemble-based Docking

A list of 27 promising antiviral drugs is proposed for use against the H1N1pdm strain. Since the binding site of the H1N1pdm neuraminidase is similar to that of the bird flu H5N1, an effective means to quickly identify top candidates for use against H1N1pdm is to use known bird-flu drugs and the 27...

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Detalles Bibliográficos
Autores principales: Nguyen, Hung, Le, Ly, Truong, Thanh N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762758/
https://www.ncbi.nlm.nih.gov/pubmed/20029612
http://dx.doi.org/10.1371/currents.RRN1030