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Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke

BACKGROUND: Minocycline, a second-generation tetracycline with anti-inflammatory and anti-apoptotic properties, has been shown to promote therapeutic benefits in experimental stroke. However, equally compelling evidence demonstrates that the drug exerts variable and even detrimental effects in many...

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Detalles Bibliográficos
Autores principales: Matsukawa, Noriyuki, Yasuhara, Takao, Hara, Koichi, Xu, Lin, Maki, Mina, Yu, Guolong, Kaneko, Yuji, Ojika, Kosei, Hess, David C, Borlongan, Cesar V
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762982/
https://www.ncbi.nlm.nih.gov/pubmed/19807907
http://dx.doi.org/10.1186/1471-2202-10-126