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Therapeutic targets and limits of minocycline neuroprotection in experimental ischemic stroke
BACKGROUND: Minocycline, a second-generation tetracycline with anti-inflammatory and anti-apoptotic properties, has been shown to promote therapeutic benefits in experimental stroke. However, equally compelling evidence demonstrates that the drug exerts variable and even detrimental effects in many...
Autores principales: | Matsukawa, Noriyuki, Yasuhara, Takao, Hara, Koichi, Xu, Lin, Maki, Mina, Yu, Guolong, Kaneko, Yuji, Ojika, Kosei, Hess, David C, Borlongan, Cesar V |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762982/ https://www.ncbi.nlm.nih.gov/pubmed/19807907 http://dx.doi.org/10.1186/1471-2202-10-126 |
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