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Epigenetic hereditary transcription profiles III, evidence for an epigenetic network resulting in gender, tissue and age-specific variation in overall transcription

BACKGROUND: We have previously shown that deviations from the average transcription profile of a group of functionally related genes are not only heritable, but also demonstrate specific patterns associated with age, gender and differentiation, thereby implicating genome-wide nuclear programming as...

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Detalles Bibliográficos
Autor principal: Simons, Johannes WIM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762993/
https://www.ncbi.nlm.nih.gov/pubmed/19796384
http://dx.doi.org/10.1186/1745-6150-4-37