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What next for preimplantation genetic screening? High mitotic chromosome instability rate provides the biological basis for the low success rate

Preimplantation genetic screening is being scrutinized, as recent randomized clinical trials failed to observe the expected significant increase in live birth rates following fluorescence in situ hybridization (FISH)-based screening. Although these randomized clinical trials are criticized on their...

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Detalles Bibliográficos
Autores principales: Vanneste, Evelyne, Voet, Thierry, Melotte, Cindy, Debrock, Sophie, Sermon, Karen, Staessen, Catherine, Liebaers, Inge, Fryns, Jean-Pierre, D'Hooghe, Thomas, Vermeesch, Joris R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763130/
https://www.ncbi.nlm.nih.gov/pubmed/19633308
http://dx.doi.org/10.1093/humrep/dep266